Barely Significant
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The apolipoprotein receptor LRP3 compromises APP levels.

Alzheimers Res Ther · 2021 · PMC8565065 · PMID 34727970

Europe PMCDOI
1
hedged sentence
0.1000
closest p · 2.0× alpha
0.1000
boldest claim

The sentences

failed to reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)
However, when cases with AD-related pathology were categorized by Braak NFT stages, the reduction was significant only at Braak stages NFT I–II ( p = 0.03; t -test), while NFT III–IV or NFT V–VI displayed the same trend but failed to reach statistical significance ( p = 0.10; p = 0.15, respectively, t -test).

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