showed a trendp = 0.062
Binary logistic regression of the NP manifestations showed a trend between seizure and deactivation and worsening group [ X 2 (1) = 3.798; p = 0.062, R 2 Negelkerke = 0.185; OR = 5.133; IC 95% = 0.922–28.570] and deactivation group [ X 2 (1) = 3.665; p = 0.096, R 2 Negelkerke = 0.185; OR = 7.000; IC 95% = 0.709–69.121], but not for the amelioration, activation and worsening (Fig. 1 ).