did not reach statistical significanceP = 0.0597
The lower facility encounter costs among engaged patients outweighed their slightly greater clinician services costs vs non-engaged patients resulting in lower overall costs of $8733 for engaged vs $11,441 for non-engaged patients, for an overall cost reduction of $2708 per patient over 9 months for engaged patients. Buprenorphine Adherence Patterns Adherence to buprenorphine therapy rose among engaged patients (pre-index mean MPR = 0.69; post-index mean MPR = 0.80, P < 0.0001) as well as among the non-engaged patients although the pre/post difference among non-engagers did not reach statistical significance (pre-index mean MPR = 0.62; post-index mean MPR = 0.79; P = 0.0597).