nominally significantP = 0.0163
Similarly, a nominally significant distribution shift was observed in hypothalamus tissue using the gene set implicated in sporadic PD ( P = 0.0163).
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Mitochondrial-nuclear cross-talk in the human brain is modulated by cell type and perturbed in neurodegenerative disease.
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0.0163
0.0500
The sentences
highly significantP < 0.05
In contrast to this, we found that genes associated with adult onset ND had highly significant differences in mitochondrial−nuclear correlations in the majority of CNS regions ( P < 0.05, Bonferroni-corrected for regions and gene sets).