As a model involving neutrophil infiltration induced by oxidative stress, the OVA + ozone group showed a trend of increased HIF-1α expression, but there was no significant difference between the OVA + ozone group and the control group ( Figure 3B ).
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STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration.
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The sentences
HIF-1α expression in the OVA + ozone group showed an increasing trend compared with that in the control group, but the difference was not significant, which may have been related to the low ozone concentration (2 ppm) used in our modeling process.