Synaptic Zn<sup>2+</sup> potentiates the effects of cocaine on striatal dopamine neurotransmission and behavior.

Transl Psychiatry · 2021 · PMC8575899 · PMID 34750356

Europe PMC DOI

hedged sentence

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

showed a trendp = 0.058so close (0.05 < p ≤ 0.1)

However, cocaine-treated WT mice ( n = 6) showed a trend toward greater [ 3 H]WIN-35,428 binding ( t = 2.21; p = 0.058) compared to vehicle-treated WT mice ( n = 6) and significantly greater [ 3 H]WIN-35,428 binding than both vehicle-treated ( n = 6) ( t = 4.14; p = 0.009) and cocaine-treated KO mice ( n = 6) ( t = 3.12; p = 0.02).

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