CYP11B1 variants influence skeletal maturation via alternative splicing.

Commun Biol · 2021 · PMC8578655 · PMID 34754074

Europe PMC DOI

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nominally significantP = 1.7 × 10 −10actually significant

The sex-stratified meta-analyses (Supplementary Data 4 ) showed nominally significant sex-heterogeneity ( P het = 0.02) for the lead SNP (rs6471570) in the CYP11B1 locus in boys ( β = 0.20; P = 1.7 × 10 −10 ) and girls ( β = 0.10; P = 0.001).

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