Frontotemporal Lobar Dementia Mutant Tau Impairs Axonal Transport through a Protein Phosphatase 1γ-Dependent Mechanism.

J Neurosci · 2021 · PMC8580143 · PMID 34607969

Europe PMC DOI

hedged sentence

0.1531

closest p · 3.1× alpha

0.1531

boldest claim

The sentences

did not reach statistical significancep = 0.1531not close (p > 0.1)

P301L tau induced a significant increase in active PP1 compared with WT tau ( p = 0.0092), and PAD deletion in a P301L background caused a ninefold reduction in active PP1γ that did not reach statistical significance ( p = 0.1531) and a return to levels that were not significantly different from WT tau ( p = 0.7579).

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