In Vitro Cartilage Regeneration with a Three-Dimensional Polyglycolic Acid (PGA) Implant in a Bovine Cartilage Punch Model.

Proteoglycan Content in Tissue Extracts and Culture Supernatant (DMB-Test) For cell-loaded PGA, the decline of the GAG concentration in the cartilage ring during culture (from 4525 μg/mL for fresh cartilage to 3853 μg/mL at 12 weeks, including an intermediate 4-week peak of 4784 μg/mL; Supplementary Figure S1B ) was limited and did not reach statistical significance.

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