In the RENEW study, both the conventional full-field VEP (which was the primary endpoint of the study) and the mfVEP latency demonstrated a larger improvement in ON eyes of patients treated with opicinumab compared to placebo ( Cadavid et al., 2017 ; Klistorner et al., 2018 ), although this only reached borderline significance.
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Role of Multifocal Visually Evoked Potential as a Biomarker of Demyelination, Spontaneous Remyelination, and Myelin Repair in Multiple Sclerosis.
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