Although TIMP-1 mRNA was increased in the 8-time UCB-Exo infusion group, this did not reach statistical significance (Fig. 5 C), whereas protein expression of TIMP-1 was inhibited by treatment with UCB-Exo for 8 times (Fig. 5 E, H).
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Umbilical cord blood plasma-derived exosomes as a novel therapy to reverse liver fibrosis.
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