The explanatory power of the PRS was close to zero in both cases (~0.02% in the pilot study; ~0.01% in the current study), but the association in the pilot study was in the opposite direction compared to the new result for ASD, and the latter was at least nominally significant, unlike the former result.
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Pleiotropy between language impairment and broader behavioral disorders-an investigation of both common and rare genetic variants.
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