Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy.

Front Pharmacol · 2021 · PMC8591126 · PMID 34790117

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slightly significantno p-value reported

There was a significant difference in cytotoxicity between EpCAM CAR T cells and mGFP CAR T cells against EpCAM-positive cell lines HCT116 and SW480 ( Figures 4C,D ), whereas the difference was not significant or was slightly significant against EpCAM-negative cells A549 and RKO ( Figures 4E,F ).

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