Suppression of ER-stress induction of GRP78 as an anti-neoplastic mechanism of the cardiac glycoside Lanatoside C in pancreatic cancer: Lanatoside C suppresses GRP78 stress induction.

Neoplasia · 2021 · PMC8591401 · PMID 34768108

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Treatment with increasing concentration of LanC under ER stress showed a trend of moderate suppression of GRP94 expression level and higher doses of LanC (0.75μM and 1μM) significantly inhibited GRP94 protein level ( Fig. 4 B).

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