Barely Significant
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First clinical expression of equine insect bite hypersensitivity is associated with co-sensitization to multiple Culicoides allergens.

PLoS One · 2021 · PMC8592417 · PMID 34780496

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Even though comparison of the percentage of IgE positive reaction between T IBH and T IBH +1 did not reach statistical significance for any Culicoides r-allergen, for many r-allergens a further increase in the number IgE positive horses was observed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.