Evolutionary and Phenotypic Characterization of Two Spike Mutations in European Lineage 20E of SARS-CoV-2.

The 20E S genotype also showed a trend toward increased infectivity versus the S:D614G replacement alone (35% increase in both cell lines), as previously reported ( 47 ), yet the difference was not statistically significant ( P = 0.2 by unpaired t test) ( Fig. 4a and b ).

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