Alternative splicing regulation of cell-cycle genes by SPF45/SR140/CHERP complex controls cell proliferation.

Interestingly, however, the AONs also caused a reduction in FOXM1 inactive isoforms in control cells, which also showed a trend toward increased clonogenic capacity ( Fig. 6 B,C), again arguing that FOXM1 AS does have an impact on cell proliferation under normal conditions.

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