Targeting the RNA-Binding Protein <i>QKI</i> in Myeloid Cells Ameliorates Macrophage-Induced Renal Interstitial Fibrosis.

Furthermore, mRNA levels of the macrophage markers F4/80 and CD115 were significantly reduced in QKI FL/FL;LysM-Cre fibrotic kidneys ( Figure 3 E), whereas the fibrosis genes α-SMA and COL1A1 only showed a trend toward reduced expression levels in QKI FL/FL;LysM-Cre UUO kidneys ( Figure 3 F).

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