nominally significantP ≤ 0.05
Of the 279 gene–trait associations for which we attempted replication, 193 (69%; 28 with a binary trait, 165 with a quantitative trait) were nominally significant ( P ≤ 0.05) and directionally consistent (Supplementary Table 6 ), versus around 7 expected by chance (279 × 0.05 × 0.5).