Reduced antibody activity against SARS-CoV-2 B.1.617.2 delta virus in serum of mRNA-vaccinated individuals receiving tumor necrosis factor-α inhibitors.

Med · 2021 · PMC8599018 · PMID 34812429

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a clear trendno p-value reported

From a cohort of 77 individuals with CID on different immunosuppressive therapies, we observed a clear trend toward lower antibody neutralizing and Fc effector function responses after two doses of Pfizer BNT162b2 mRNA vaccination in those receiving TNFi.

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