Pegylated Interferon Treatment for the Effective Clearance of Hepatitis B Surface Antigen in Inactive HBsAg Carriers: A Meta-Analysis.

Front Immunol · 2021 · PMC8600041 · PMID 34804072

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did not reach statistical significanceP =0.5not close (p > 0.1)

The HBsAg clearance rates were 29% (95% CI: 17% - 40%) after 24 weeks of treatment, 39% (95% CI: 25% - 53%) after 48 weeks of treatment, and 43% (95% CI: 35% - 50%) after 96 weeks of treatment ( Figure S3 ), suggesting that HBsAg clearance increased with longer Peg-IFN treatment, although the difference did not reach statistical significance ( P =0.5).

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