Glycan Biosynthesis Ability of Gut Microbiota Increased in Primary Hypertension Patients Taking Antihypertension Medications and Potentially Promoted by Macrophage-Adenosine Monophosphate-Activated Protein Kinase.

Meanwhile, we also calculated α-diversity by Simpson and Evenness indexes, and these two indexes were also lower in the HBP group at all three levels but did not reach statistical significance ( Supplementary Figure 1 ).

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Statistical analysis found that there were 38 ortholog groups significantly (or almost significant) enriched in the HBP group (summarized in Supplementary Table 6 ), and there were four ortholog groups significantly enriched in healthy control.

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