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Trend analysis of carbapenem-resistant Gram-negative bacteria and antimicrobial consumption in the post-COVID-19 era: an extra challenge for healthcare institutions.

J Hosp Infect · 2022 · PMC8603865 · PMID 34808311

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an increasing trendno p-value reported
Interestingly, some antimicrobials revealed an increasing trend in consumption in DDD per 1000 patient-days.

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a marked trendno p-value reported
We believe that our study identifies a marked trend of change in the resistance profile in DAIs as well as in antimicrobial consumption since the onset of the COVID-19 pandemic, which is an alarm for healthcare institutions and government agencies regarding the need to focus efforts for investigation and control, especially against a scenario of scarce resources.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.