Although several nominally significant associations were observed between modules and various histopathological features (Fig. 2b ), only positive correlations between M4/ulceration and M6/lymphoid aggregates remained significant after adjusting for multiple testing ( P adjusted < 0.05; Fig. 2b ).
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IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies.
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