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Intrinsic Defects in B Cell Development and Differentiation, T Cell Exhaustion and Altered Unconventional T Cell Generation Characterize Human Adenosine Deaminase Type 2 Deficiency.

J Clin Immunol · 2021 · PMC8604888 · PMID 34657246

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Granzyme B secretion by ADA2-deficient CD8 + T cells tended to be reduced but did not reach statistical significance (Fig. 5B ).

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