In contrast, remdesivir use showed a trend to lower mortality risk (aHR, 0.48; 95% CI, 0.23–1.02) ( Figure 1 ).
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Impact of the Addition of Baricitinib to Standard of Care Including Tocilizumab and Corticosteroids on Mortality and Safety in Severe COVID-19.
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Thereafter, all of them showed a decreasing trend with minor differences in the trajectories between treatment groups and initial small and transient increases in the levels of IL-6 and D-dimer ( Figure 4 ).