Barely Significant
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Assessing Genetic Overlap and Causality Between Blood Plasma Proteins and Alzheimer's Disease.

J Alzheimers Dis · 2021 · PMC8609677 · PMID 34459398

Europe PMCDOI
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closest p · 1.0× alpha
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The sentences

nominally significantp < 0.05actually significant
Given this is a conservative threshold, if no proteins pass this threshold in all participants (APOE+ and APOE–), nominally significant proteins ( p < 0.05) will be considered for MR analysis based on an assessment of their association strength (e.g., how close to Bonferroni threshold) and consistency (e.g., association across subgroups).

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