Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies.

Sci Adv · 2021 · PMC8612689 · PMID 34818048

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a clear trendno p-value reported

A clear trend of a progressive decrease of both components was observed for POM2, yet not for POM1, thus further supporting the abovementioned AFM findings of strong aggregation of POM2/recPrP complexes.

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