Comparison of Different Systemic Therapeutic Regimes in Resectable Soft-Tissue Sarcoma-Results of a Network Meta-Analysis.

Cancers (Basel) · 2021 · PMC8615898 · PMID 34830786

Europe PMC DOI

hedged sentence

0.1950

closest p · 3.9× alpha

0.1950

boldest claim

The sentences

did not reach statistical significancep = 0.195not close (p > 0.1)

Neoadjuvant chemotherapy (direct comparison, 1 trial) and perioperative chemotherapy (indirect comparison) had higher effect sizes than adjuvant chemotherapy, but did not reach statistical significance ((HR = 0.61, CI-95%: 0.29–1.29, p = 0.195) and (HR = 0.66; CI-95%: 0.30–1.48; p = 0.317)).

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