Although the A allele of rs4293393 and T allele of rs6497476 was shown to be associated with higher levels of both eGFR and serum uromodulin, the differences did not reach statistical significance due to the corresponding alleles accounting for the majority of the population ( Figure 2 ).
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<i>UMOD</i> Polymorphisms Associated with Kidney Function, Serum Uromodulin and Risk of Mortality among Patients with Chronic Kidney Disease, Results from the C-STRIDE Study.
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