Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation.

Pharmaceuticals (Basel) · 2021 · PMC8622821 · PMID 34832855

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a slight trendno p-value reported

Our results showed that Iba1 protein expression increased significantly in the TGs of CFA-treated animals at day 5, while the mRNA expression of this target showed a slight trend of increase at day 14 ( Figure 6 A,C).

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showed a trendno p-value reported

The CFA model showed a trend of increased levels of the major sensory neuropeptide CGRP and Iba1 expression, both of which are indicative of neuronal sensitization and inflammation, which have been associated with pain.

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