Role of Sex on the Genetic Susceptibility to Childhood Asthma in Latinos and African Americans.

The asthma-associated variants in 2p21 near LDHAP3 , a locus previously associated with severe asthma exacerbations in Latinos from GALA II [ 25 ], had a predominant effect in males and were nominally significant in the interaction and female-only analyses ( p -value < 0.05) ( Table 3 and Table S3 ).

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