Converging Effects of Three Different Endocrine Disrupters on Sox and Pou Gene Expression in Developing Rat Hippocampus: Possible Role of microRNA in Sex Differences.

According to real time RT PCR analysis, the lower dose of the three treatments may also have been active, but the effect did not reach statistical significance ( Figure 3 ).

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FPKM values of individual hippocampus samples from male offspring of controls and high-dose treatment groups revealed a highly significant inverse correlation between Pvalb and Sox6, whereas no such correlation was seen between individual values of Sox6 and neuronal nitric oxide synthase (Nos1) or between Sox6 and the serotonergic ionotropic receptor Htr3a ( Figure 6 ).

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