Aggressiveness of care at end of life in patients with high-grade glioma.

When evaluating the latency between the first time pain, distress, depressive symptoms, neglect, or abuse were documented in the chart and PC referral, there was a nonsignificant trend toward shorter latency in HGG patients (45.5 ± 76.6 weeks) compared with non‐CNS cancer patients (75.8 ± 129 weeks, p = 0.277).

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In analyzing those patients that saw PC univariately, more severe symptoms related to appetite ( p = 0.049) and shortness of breath ( p = 0.006) on the ESAS (Edmonton Symptom Assessment System) were associated with less aggressive EoL care, and higher pain scores ( p = 0.058) approached significance.

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