MCP-1, which is responsible for the recruitment of monocytes to the site of inflammation ( 24 ), was increased in lean mice 1 h post trauma but did not reach statistical significance ( Figure 5H ); similar results were also received for obese mice 6 h post trauma.
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Obesity Prolongs the Inflammatory Response in Mice After Severe Trauma and Attenuates the Splenic Response to the Inflammatory Reflex.
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