Macular thickness varies with age-related macular degeneration genetic risk variants in the UK Biobank cohort.

We identified several nominally significant associations with average SD-OCT measurements (Table 1 , Supplementary Table S2 ), of which 10 remained significant after multiple testing corrections (p < 0.0004 (0.05/(4 × 33).

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ISOS-RPE thinning was the most highly significant change seen in our PRS analysis with presence of AMD risk SNPs.

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