Secreted frizzled related-protein 2 (Sfrp2) deficiency decreases adult skeletal stem cell function in mice.

Treatment of the silenced cells with rm-Sfrp2 for 5 h showed a trend to increase pLrp6, and at 24 h, restored Axin2 expression, with a very modest increase in C-myc , but no increase in Cyclin D1 expression (Fig. 6c, d ).

also in 53,322 other papers