Lymphovascular invasion has a significant prognostic impact in patients with early breast cancer, results from a large, national, multicenter, retrospective cohort study.

ESMO Open · 2021 · PMC8645922 · PMID 34864349

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

However, in patients with AC (3876), only DFS (HR = 1.288, 95% CI 1.070-1.550; P = 0.008) and MFS (HR = 1.331, 95% CI 1.029-1.721; P = 0.029) were associated with a negative impact of LVI, while OS did not reach statistical significance (HR = 1.279, 95% CI 0.990-1.651; P = 0.06).

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