Importantly, type A TDP‐43‐HA neoaggregates showed higher density of particles compared to type C (Fig 4G and H ), albeit this observation did not reach statistical significance when we probed phosphorylated TDP‐43 pS403/404 neoaggregates (Fig EV2D ).
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FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade.
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