In LUAD, IL1β was positively associated with GLUT1 ( r =0.243, P <0.001), GLUT3 ( r =0.453, P <0.001), HK2 ( r =0.33, P <0.001), PFKL ( r =0.138, P =0.002), PKM2 ( r =0.135, P =0.002), MCT1 ( r =0.349, P <0.001), and LDHA ( r =0.21, P <0.001) in GEPIA, but the relationship between IL1β and MCT4 did not reach statistical significance (=−0.062, P =0.159; Figure 1C ).
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Interleukin -1β Promotes Lung Adenocarcinoma Growth and Invasion Through Promoting Glycolysis via p38 Pathway.
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