Functional enrichment analysis in sputum cells highlighted a clear trend toward decreased inflammatory conditions with a significant modulation of key COPD pathways involved in cytokine activity, pathogen-associated-pattern-recognition activity, oxidative stress and vitamin D with associated inhibition of downstream inflammatory effectors ( Govoni et al., 2020 ).
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Tanimilast, A Novel Inhaled Pde4 Inhibitor for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease.
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