Mesenchymal stem cell transplantation after acute myocardial infarction: a meta-analysis of clinical trials.

The change in LVESV, as a pooled analysis of six studies, was not significant (WMD = − 2.892 ml, 95%Cl, − 6.779 to 0.995, p value = 0.145, I 2 = 38.4%) and after excluding the three studies with high risk of bias, the reduction was greater and still marginally nonsignificant (WMD = − 5.963 ml, 95% CI, − 12.18 to 0.26, p value = 0.17, I 2 = 43.8%); (Additional file 1 ).

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Meta-regression analysis Meta-regression analyses for age (Additional file 6 ), follow-up duration, transplant time, cell number, and the baseline values did not show a significant trend for LVEF either in presence or after excluding high risk of bias studies.

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