The endogenous HeT-A elements are de-repressed in either a hiphop or a piRNA defective background ( spnE - ), while a gfp -marked HeT-A transgene is only de-silenced under the latter since the slight elevation of HeT-A GFP expression under the hiphop HA/df background did not reach statistical significance ( Fig 3A ).
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Taming active transposons at Drosophila telomeres: The interconnection between HipHop's roles in capping and transcriptional silencing.
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