In contrast, C57BL/6 are largely tolerable to various dosages of Dex with minimal changes in bone mass except for a slight trend of dose-dependent loss ( Figure 1B ).
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A Core Omnigenic Non-coding Trait Governing Dex-Induced Osteoporotic Effects Identified Without DEXA.
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There is a clear trend of increase in these immune-related genes in the stromal progenitors from day 2 towards day 18, where the protein-protein interactions among these genes marked up a co-expressed, interactive network with predictive value of the tendency of bone mineralization among CC mice calvaria osteoblasts ( Figure 3C ).