Barely Significant
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Phosphodiesterase-4 Inhibition Reduces Cutaneous Inflammation and IL-1β Expression in a Psoriasiform Mouse Model but Does Not Inhibit Inflammasome Activation.

Int J Mol Sci · 2021 · PMC8657753 · PMID 34884681

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a clear trendno p-value reported
IL6 and NLRP3 showed a clear trend of decreased expression, however, this was not statistically significant.

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