Long-term, stable, targeted biodelivery and efficacy of GDNF from encapsulated cells in the rat and Goettingen miniature pig brain.

Although a trend towards a deficit was seen in the GDNF-treated animals at 4 weeks post lesion, this effect did not reach statistical significance ( Fig. 5 d; p<0.10). 3.5 Neurorecovery The studies evaluated the ability of cell-based GDNF, to promote neurological recovery following loss of dopaminergic neurons.

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