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Dysbiosis and relapse-related microbiome in inflammatory bowel disease: A shotgun metagenomic approach.

Comput Struct Biotechnol J · 2021 · PMC8665270 · PMID 34938418

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Only one pathway in samples at baseline (patients with active disease, n = 21) showed a trend towards enrichment (lactate consumption II, FDR = 0.13) compared to samples from patients who remained in remission 6 months after surgery (n = 28). 3.4 Predictive value of the microbiome data to discriminate IBD from non-IBD, and relapse from remission To assess the predictive value of the microbial signatures discovered and their consistency between cohorts, we built random forest models based on the abundance of microbiome species to predict health status and disease activity.

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