Citrate supplementation did not significantly affect food intake or body weight of flies, although there was a small trend toward reduced food intake and body weight in both sexes of flies treated with the higher concentrations of citrate (Figure 1c,d ).
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Dietary citrate supplementation enhances longevity, metabolic health, and memory performance through promoting ketogenesis.
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The sentences
Mice treated with 1% citrate showed a trend toward higher oxygen consumption and CO 2 production, and thus toward slightly higher energy expenditure, in the dark phase of the light‐dark cycle, which could contribute to the lower body weight gain observed (Figures 4a,b ,e and S6 a,b).