The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans.

Results Clinical Responses to Pioglitazone Treatment In agreement with the established clinical effects of thiazolidinediones ( Aronoff et al., 2000 ; Miyazaki et al., 2001 ), 6months of pioglitazone treatment lowered fasting blood glucose ( Figure 1A ) and HbA1c ( Figure 1B ), although the decline in fasting triglycerides ( Figure 1C ) did not reach statistical significance ( p =0.085).

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