The Bx genotype was found to be more frequent in mild disease cases compared to the AA genotype (34.38% vs 25.74%), while in severe disease cases the AA genotype was more common than the Bx genotype (49.26% vs 44.44%) but these differences did not reach statistical significance ( Table 4 ). 4 Discussion A better understanding of the genetic factors underlying the extremely heterogeneous phenotypic response to infection with SARS-CoV-2 in humans is crucial for both future diagnostics and the development of treatment options.
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